Friday, May 6, 2011

Tradjenta- A new type 2 diabetes pills approved by FDA

A new drug manufactured by Boehringer Ingelheim and Elly Lilly, Tradjenta also known by the generic name linagliptin has been approved recently by FDA (Food and Drug Administration). The pill helps to control blood sugar in adults with type 2 diabetes, which is the most general form of the disease that affects 90-95% of the 24 million people in the US. Tradjenta tablets can be used together with diet and exercise.

Tradjenta- A new Drug approved by FDA

How Tradjenta works?

The drug works by blocking the enzyme dipeptidyl peptidase-4 (DPP-4) for raising the levels of insulin-stimulating hormones in the body. Improved blood sugar control can be experienced by patients through encouraging the discharge of insulin after a meal. The new drug has been approved as a stand-alone therapy or in grouping with older diabetes drugs such as metformin, sulfonylurea and pioglitazone.

FDA study:

The FDA told that Linagliptin was studied in around 4000 patients with type 2 diabetes and was superior to placebo in controlling glucose. Linagliptin was exposed to decrease hemoglobin A1C (HbA1C or A1C) levels equal to 0.7% in comparison to placebo. How much the diabetes patient has been proficient to control blood sugar in the last 2-3 months is being indicated by A1C. Individuals who have diabetic ketoacidosis or type 1 diabetes must not take Tradjenta. It is not known whether the drug is safe and effectual for children and when used with insulin.

When the drug is allotted, an FDA-approved Patient Package Insert will be included that signifies the medication's uses and risks. Upper respiratory tract infection, sore throat, muscle pain, stuffy or runny nose, and headache are the general side effects of the drug, however not anything main. Tradjenta is marketed by Boehringer Ingelheim Pharmaceuticals Inc., based in Ridgefield, Conn. and Eli Lilly & Co. Inc. based in Indianapolis.

Ingredients and dosage of Tradjenta:

The ingredients in Tradjenta include linagliptin - Active Ingredient whereas corn starch, copovidone, mannitol, pregelatinized starch, and magnesium stearate - Inactive Ingredients. Some other inactive ingredients contained in the film coating are talc, polyethylene glycol, hypromellose, titanium dioxide, and red ferric oxide.
Tradjenta 5 mg once a day has been approved. Consult your doctor before taking Tradjenta if you are pregnant or plan to become pregnant, breastfeeding or plan to breastfeed, or have any other medical conditions. Also discuss with your doctor if you consume other medicines like vitamins, herbal supplements, prescription and non-prescription medicines, and medicines that can lower your blood sugar. Hunger, fast heart beat, weakness, dizziness, headache, drowsiness, confusion, irritability, sweating, or feeling jittery are the signs and symptoms of low blood sugar.


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